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洛阳市中心医院肿瘤绿色治疗又添新技术——成功完成一例肺转移癌电冷消融手术

  • 2026-02-16 19:08:29
洛阳市中心医院肿瘤绿色治疗又添新技术——成功完成一例肺转移癌电冷消融手术

肿瘤“绿色治疗”是我院肿瘤一区的学术名片，更是地市级医疗平台中独具特色的一环。

近5年来，我院肿瘤一区采用局部微创技术联合全身中药的治疗模式，将癌症视为一种慢性病，为失去手术机会、不能耐受放化疗及术后复发的患者提供了一种很好的治疗选择。

截至目前，接受“绿色治疗”的患者超过百例，患者从治疗中获益良多。

新技术

为进一步提升“绿色治疗”的效果，我院肿瘤一区不断引进和创新现代微创技术。“绿色治疗”需要多种现代微创技术的支撑，在康博刀冷消融、微波热消融、经血管介入等基础之上，科室又新添前沿消融技术——电冷复合消融技术。
电冷复合消融技术是将电化学消融与冷冻消融相结合的新型肿瘤微创消融技术，适用于治疗各种实体恶性肿瘤组织。冷冻消融通过肿瘤局部超低温（-145℃）引起肿瘤的物理性坏死或代谢性损伤；电化学消融通过阳极探针将直流电流传递并局限在冷冻治疗病灶范围内，引起冷冻范围内局部的PH值变化而形成细胞毒素环境，快速杀死冷冻范围内的肿瘤细胞，防止残留。
相比传统的冷冻消融技术，电冷消融具有在冷冻范围内部导电的特性，通过冷冻区域内阴极针（阴极PH值11-13）和阳极针（阳极PH值1-2）之间质子和离子的运动造成局部酸碱环境的极具变化、细胞通透性改变等直接杀伤肿瘤细胞，克服了传统的冷冻消融不完全的弊端，有望解决局部肿瘤残留复发的难题。
目前，我院“临床试验中心”正在进行针对肺癌和肺转移癌的电冷复合消融的临床研究。

案例

近期，我院肿瘤科裴志东主任团队为一例甲状腺癌肺转移患者成功实施了肺部病灶电冷消融术，这是我院开展的首例电冷复合消融术，手术持续120分钟，操作过程安全可控，术中术后生命体征平稳。

患者为老年男性，甲状腺癌术后10年出现肺转移，多次碘131治疗，全身化疗、靶向治疗、免疫治疗等都不能控制肺内病灶。老人因肺部转移瘤较大，加之全身多发骨转移、基础条件差、肺功能低下和高龄等诸多难题，无法手术切除。针对该患者的病情，裴志东主任团队经过充分的术前讨论，与患者及家属详细沟通，并对术中、术后可能发生的风险制定了细致的应对处置预案，最终决定针对左肺病灶行电冷复合消融术。

术中穿刺

术中消融

患者病灶位于左下肺，大小8.5*5.6cm，患者俯卧位CT扫描定位，左下肺可见肿块影，局部麻醉后，按照手术设计穿刺路径，分别将阳极针、阴极针经皮穿刺进入病灶，通过冷消融4个循环、电解消融1个循环后，CT扫描可见肺内病灶坏死明显，手术2小时后顺利结束。术后病人无不适症状，3天后好转出院。
本次电冷复合消融技术的顺利实施是该项技术的又一成功案例，为广大癌症患者带来希望！这也是我院肿瘤一区“绿色治疗”模式的又一创新，体现了我院肿瘤科医务人员为患者的健康坚苦奋斗的精神，在此衷心祝愿每一位癌症患者都能早日康复，重获新生！
来源：肿瘤一 郑跃辉
编辑：宣传科 樊梦真
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  1. CONNECT:[ UseTime:0.000546s ] mysql:host=127.0.0.1;port=3306;dbname=i460;charset=utf8mb4
  2. SHOW FULL COLUMNS FROM `fenlei` [ RunTime:0.000646s ]
  3. SELECT * FROM `fenlei` WHERE `fid` = 0 [ RunTime:0.000240s ]
  4. SELECT * FROM `fenlei` WHERE `fid` = 63 [ RunTime:0.000284s ]
  5. SHOW FULL COLUMNS FROM `set` [ RunTime:0.000649s ]
  6. SELECT * FROM `set` [ RunTime:0.002301s ]
  7. SHOW FULL COLUMNS FROM `article` [ RunTime:0.000545s ]
  8. SELECT * FROM `article` WHERE `id` = 468112 LIMIT 1 [ RunTime:0.000375s ]
  9. UPDATE `article` SET `lasttime` = 1771793838 WHERE `id` = 468112 [ RunTime:0.006763s ]
  10. SELECT * FROM `fenlei` WHERE `id` = 65 LIMIT 1 [ RunTime:0.000266s ]
  11. SELECT * FROM `article` WHERE `id` < 468112 ORDER BY `id` DESC LIMIT 1 [ RunTime:0.000511s ]
  12. SELECT * FROM `article` WHERE `id` > 468112 ORDER BY `id` ASC LIMIT 1 [ RunTime:0.000428s ]
  13. SELECT * FROM `article` WHERE `id` < 468112 ORDER BY `id` DESC LIMIT 10 [ RunTime:0.000806s ]
  14. SELECT * FROM `article` WHERE `id` < 468112 ORDER BY `id` DESC LIMIT 10,10 [ RunTime:0.000787s ]
  15. SELECT * FROM `article` WHERE `id` < 468112 ORDER BY `id` DESC LIMIT 20,10 [ RunTime:0.004661s ]
0.139147s